ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

Whilst the ChAdOx1 nCoV-19 (AZD1222) vaccine has demonstrated efficacy against symptomatic disease, variants of concern (VOCs) with spike protein substitutions have led researchers to explore updating vaccines from ancestral spike protein. Authors use a Syrian hamster model to evaluate a vaccine enc...

Full description

Bibliographic Details
Main Authors: Neeltje van Doremalen, Jonathan E. Schulz, Danielle R. Adney, Taylor A. Saturday, Robert J. Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J. Spencer, Dalan Bailey, Colin A. Russell, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32248-6

Internet

https://doi.org/10.1038/s41467-022-32248-6

Similar Items