In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics

In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics

New variants of SARS-CoV-2 continue to evolve. The novel SARS-CoV-2 variant of concern (VOC) B.1.1.529 (Omicron) was particularly menacing due to the presence of numerous consequential mutations. In this study, we reviewed about 12 million SARS-CoV-2 genomic and associated metadata using extensive b...

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Bibliographic Details
Main Authors: Dhruv Chauhan, Nikhil Chakravarty, Arjit Vijey Jeyachandran, Akshaya Jayakarunakaran, Sanjeev Sinha, Rakesh Mishra, Vaithilingaraja Arumugaswami, Arunachalam Ramaiah
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
SARS-CoV-2
Omicron
COVID-19
evolution
receptor binding domain
T-cell epitope
Online Access:https://www.mdpi.com/1999-4915/14/11/2461

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https://www.mdpi.com/1999-4915/14/11/2461

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