Rational construction of genome-reduced and high-efficient industrial Streptomyces chassis based on multiple comparative genomic approaches

Rational construction of genome-reduced and high-efficient industrial Streptomyces chassis based on multiple comparative genomic approaches

Abstract Background Streptomyces chattanoogensis L10 is the industrial producer of natamycin and has been proved a highly efficient host for diverse natural products. It has an enormous potential to be developed as a versatile cell factory for production of heterologous secondary metabolites. Here w...

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Bibliographic Details
Main Authors: Qing-Ting Bu, Pin Yu, Jue Wang, Zi-Yue Li, Xin-Ai Chen, Xu-Ming Mao, Yong-Quan Li
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Microbial Cell Factories
Subjects:
Streptomyces chattanoogensis
Cell factory
Computational approaches
Cre/loxP recombination system
Biological performances
Genome-reduced chassis
Online Access:http://link.springer.com/article/10.1186/s12934-019-1055-7

Internet

http://link.springer.com/article/10.1186/s12934-019-1055-7

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