Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species.

Systematic differentiation of amyloid (Aβ) species could be important for diagnosis of Alzheimer's disease (AD). In spite of significant progress, controversies remain regarding which species are the primary contributors to the AD pathology, and which species could be used as the best biomarker...

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Bibliographic Details
Main Authors: Chongzhao Ran, Wei Zhao, Robert D Moir, Anna Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084834?pdf=render