Fetal Central Nervous System Derived Extracellular Vesicles: Potential for Non-invasive Tracking of Viral Mediated Fetal Brain Injury

Fetal Central Nervous System Derived Extracellular Vesicles: Potential for Non-invasive Tracking of Viral Mediated Fetal Brain Injury

Introduction: Extracellular vesicles derived from the fetal central nervous system (FCNSEs) can be purified from maternal serum or plasma using the protein Contactin-2/TAG1that is expressed almost exclusively by developing neurons in the hippocampus, cerebral cortex and cerebellum. We hypothesized t...

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Bibliographic Details
Main Authors: Laura Goetzl, Angela J. Stephens, Yechiel Schlesinger, Nune Darbinian, Nana Merabova, Miriam Hillel, Alec J. Hirsch, Daniel N. Streblow, Antonio E. Frias, Victoria H. J. Roberts, Nicole N. Haese, Arunmani Mani, Yifat Eldar-Yedidia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Virology
Subjects:
exosomes/extracellular vesicles (EVs/ECVs)
cytomegalovirus (CMV)
Zika (ZIKV)
Contactin-2
prenatal diagnosis
microcephaly
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2021.782863/full

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https://www.frontiersin.org/articles/10.3389/fviro.2021.782863/full

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