Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein

Abstract Nanodisc technology has dramatically advanced the analysis of molecular interactions for membrane proteins. A nanodisc is designed as a vehicle for membrane proteins that provide a native-like phospholipid environment and better thermostability in a detergent-free buffer. This enables the d...

Full description

Bibliographic Details
Main Authors: Fuhito Nakagawa, Marin Kikkawa, Sisi Chen, Yasuomi Miyashita, Norie Hamaguchi-Suzuki, Minami Shibuya, Soichi Yamashita, Lisa Nagase, Satoshi Yasuda, Mitsunori Shiroishi, Toshiya Senda, Keisuke Ito, Takeshi Murata, Satoshi Ogasawara
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38547-2