Real-Time PCR Assays for the Quantification of HCV RNA: Concordance, Discrepancies and Implications for Response Guided Therapy.

BACKGROUND AND AIMS:Monitoring of chronic Hepatitis C (CHC) treatment relies on HCV RNA quantification by means of real-time PCR methods. Assay specific analytical sensitivities may impact therapy management. METHODS:Comparative analysis between three commercial assays (Roche COBAS AmpliPrep/COBAS T...

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Bibliographic Details
Main Authors: Robert Strassl, Karoline Rutter, Albert Friedrich Stättermayer, Sandra Beinhardt, Michael Kammer, Harald Hofer, Peter Ferenci, Theresia Popow-Kraupp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4537232?pdf=render