Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach

3-dimensional domain swapping is a mechanism where two or more protein molecules form higher order oligomers by exchanging identical or similar subunits. Recently, this phenomenon has received much attention in the context of prions and neuro-degenerative diseases, due to its role in the functional...

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Bibliographic Details
Main Authors: Khader Shameer, Ganesan Pugalenthi, Krishna Kumar Kandaswamy, Ponnuthurai N. Suganthan, Govindaraju Archunan, Ramanathan Sowdhamini
Format: Article
Language:English
Published: SAGE Publishing 2010-06-01
Series:Bioinformatics and Biology Insights
Online Access:http://la-press.com/insights-into-protein-sequence-and-structure-derived-features-mediatin-a2124