<i>Caesalpinia sappan</i> Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells

<i>Caesalpinia sappan</i> Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells

Allergic rhinitis (AR) is a common upper-airway inflammatory disease of the nasal mucosa caused by immunoglobulin (IgE)-mediated inflammation. AR causes various painful clinical symptoms of the nasal mucosa that worsen the quality of daily life, necessitating the urgent development of therapeutic ag...

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Bibliographic Details
Main Authors: Bo-Jeong Pyun, Kyuhyung Jo, Joo Young Lee, Ami Lee, Myung-A Jung, Youn-Hwan Hwang, Dong Ho Jung, Kon-Young Ji, Susanna Choi, Yun Hee Kim, Taesoo Kim
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
<i>Caesalpinia sappan</i> Linn.
allergic rhinitis
Th2 cytokine
ROS
inflammation
antioxidant
Online Access:https://www.mdpi.com/2076-3921/11/11/2256

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https://www.mdpi.com/2076-3921/11/11/2256

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