Engineered osteoclasts as living treatment materials for heterotopic ossification therapy

Heterotopic ossification (HO) is the formation of pathological mature bone within extraskeletal soft tissues, and there are currently no reliable methods for removing these calcified plaques. Here, the authors demonstrate that chemically engineered osteoclasts coated with tetracycline can improve th...

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Bibliographic Details
Main Authors: Wenjing Jin, Xianfeng Lin, Haihua Pan, Chenchen Zhao, Pengcheng Qiu, Ruibo Zhao, Zihe Hu, Yanyan Zhou, Haiyan Wu, Xiao Chen, Hongwei Ouyang, Zhijian Xie, Ruikang Tang
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26593-1