COCRISTAIS: UMA ESTRATÉGIA PROMISSORA NA ÁREA FARMACÊUTICA

COCRISTAIS: UMA ESTRATÉGIA PROMISSORA NA ÁREA FARMACÊUTICA

Pharmaceutical cocrystals have emerged as a useful strategy to improve the aqueous solubility of poorly water soluble drugs by aiming to enhance their oral absorption and bioavailability. Aqueous cocrystal solubility can be orders of magnitude higher than that of the constituent drug and this solubi...

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Bibliographic Details
Main Authors: Alanny B. O. Rocha, Gislaine Kuminek, Tatiane C. Machado, Juliana Rosa, Gabriela S. Rauber, Paola A. A. Borba, Sana Siedler, Hellen K. Stulzer, Silvia Lucia Cuffini, Naír Rodríguez-Hornedo, Simone G. Cardoso
Format: Article
Language:English
Published: Sociedade Brasileira de Química
Series:Química Nova
Subjects:
cocrystals
drug
solubility
transition point
thermodynamic stability
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000901112&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000901112&lng=en&tlng=en

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