Case Report: Effectiveness of secukinumab in systemic sclerosis with early skin progress after autologous hematopoietic stem cell transplantation and end-stage kidney disease

Case Report: Effectiveness of secukinumab in systemic sclerosis with early skin progress after autologous hematopoietic stem cell transplantation and end-stage kidney disease

Autologous hematopoietic stem cell transplantation (aHSCT) represents an effective treatment option in patients with severe forms of systemic sclerosis (SSc) by resetting the immune system. Nevertheless, secondary autoimmune disorders and progressive disease after aHSCT might necessitate renewed imm...

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Bibliographic Details
Main Authors: Patrick-Pascal Strunz, Hannah Labinsky, Lea-Kristin Nagler, Jan Portegys, Matthias Froehlich, Michael Gernert, Marc Schmalzing
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
scleroderma
IL-17 inhibition
melphalan
high-dose chemotherapy
renal failure
hemodialysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1294496/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1294496/full

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