L1CAM deployed perivascular tumor niche promotes vessel wall invasion of tumor thrombus and metastasis of renal cell carcinoma
Abstract The survival of tumor cells in the bloodstream, and vasculature adhesion at metastatic sites are crucial for tumor metastasis. Perivascular invasion aids tumor cell self-renewal, survival, and formation of metastases by facilitating readily available oxygen, nutrients, and endothelial-deriv...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01410-4 |