Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage <subtitle>a new tool for cartilage pathophysiology studies</subtitle>

AimsAfter a few passages of in vitro culture, primary human articular chondrocytes undergo senescence and loss of their phenotype. Most of the available chondrocyte cell lines have been obtained from cartilage tissues different from diarthrodial joints, and their utility for osteoarthritis (OA) rese...

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Main Authors: María Piñeiro-Ramil, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Carlos Vaamonde-García, Silvia Díaz-Prado
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2023-01-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.121.BJR-2022-0207.R1