Ascorbic acid mitigates the impact of oxidative stress in a human model of febrile seizure and mesial temporal lobe epilepsy

Abstract Prolonged febrile seizures (FS) in children are linked to the development of temporal lobe epilepsy (MTLE). The association between these two pathologies may be ascribed to the long-term effects that FS exert on neural stem cells, negatively affecting the generation of new neurons. Among th...

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Bibliographic Details
Main Authors: Stefania Scalise, Clara Zannino, Valeria Lucchino, Michela Lo Conte, Vittorio Abbonante, Giorgia Lucia Benedetto, Mariangela Scalise, Antonio Gambardella, Elvira Immacolata Parrotta, Giovanni Cuda
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-56680-4