Sorafenib maintenance after allogeneic stem cell transplantation in patients with FLT3+ AML receiving midostaurin during induction and consolidation: a retrospective analysis

Sorafenib maintenance after allogeneic stem cell transplantation in patients with FLT3+ AML receiving midostaurin during induction and consolidation: a retrospective analysis

IntroductionAcute myeloid leukemia (AML) relapse is the main cause of death after allogeneic stem cell transplant (allo-SCT). In AML FLT3+, it was shown that Sorafenib used as maintenance therapy after allo-SCT, significantly reduces the risk of relapse and death. MethodsWe analyzed 29 adult patient...

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Bibliographic Details
Main Authors: Giuseppe Sapienza, Marta Castronovo, Stefania Tringali, Roberto Bono, Cristina Rotolo, Antonino Mulè, Valeria Calafiore, Caterina Patti, Cecilia Agueli, Valentina Randazzo, Alessandra Santoro, Domenica Matranga, Luca Castagna
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Oncology
Subjects:
acute myeloid leukemia (AML)
relapse
sorafenib
allogeneic stem cell transplantation (Allo-SCT)
maintenance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1441254/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1441254/full

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