Targeting the TAM Receptors in Leukemia

Targeting the TAM Receptors in Leukemia

Targeted inhibition of members of the TAM (TYRO-3, AXL, MERTK) family of receptor tyrosine kinases has recently been investigated as a novel strategy for treatment of hematologic malignancies. The physiologic functions of the TAM receptors in innate immune control, natural killer (NK) cell different...

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Bibliographic Details
Main Authors: Madeline G. Huey, Katherine A. Minson, H. Shelton Earp, Deborah DeRyckere, Douglas K. Graham
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Cancers
Subjects:
TYRO3
AXL
MERTK
Gas6
leukemia
multiple myeloma
tyrosine kinase inhibitor
resistance
hematopoiesis
signaling pathways
Online Access:http://www.mdpi.com/2072-6694/8/11/101

Internet

http://www.mdpi.com/2072-6694/8/11/101

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