Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression

Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression

ABSTRACTThis study examined the effects of methyltransferase-like 3 (METTL3) on ferroptosis during intracerebral hemorrhage (ICH) progression. The brain microvascular endothelial cells (BMVECs) were stimulated with oxygen and glucose deprivation (OGD) and hemin to establish an ICH model. Cell viabil...

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Bibliographic Details
Main Authors: Liu Zhang, Xiangyu Wang, Wenqiang Che, Yongjun Yi, Shuoming Zhou, Yongjian Feng
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
Intracerebral hemorrhage
METTL3
GPX4
ferroptosis
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2084494

Internet

https://www.tandfonline.com/doi/10.1080/21655979.2022.2084494

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