Metabolic Reprogramming of Ovarian Cancer Spheroids during Adhesion

Metabolic Reprogramming of Ovarian Cancer Spheroids during Adhesion

Ovarian cancer remains a deadly disease and its recurrence disease is due in part to the presence of disseminating ovarian cancer aggregates not removed by debulking surgery. During dissemination in a dynamic ascitic environment, the spheroid cells’ metabolism is characterized by low respiration and...

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Bibliographic Details
Main Authors: Stephanie L. E. Compton, Joseph P. Grieco, Benita Gollamudi, Eric Bae, Jennifer H. Van Mullekom, Eva M. Schmelz
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
ovarian cancer
metabolism
respiration
glucose uptake
glutamine
spheroid
Online Access:https://www.mdpi.com/2072-6694/14/6/1399

Internet

https://www.mdpi.com/2072-6694/14/6/1399

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