Design of Adenovirus 5 Vector with Adenovirus 26 Hexon Hypervariable Region Sequence using In Silico Approach
Adenovirus type 5 (Ad5) is one of the vaccine vectors, including the COVID-19 vaccine. Pre-existing immunity to Ad5 may suppress the immunogenicity and efficacy of adenovirus vectored vaccine. The neutralizing antibodies are directed specifically toward seven hypervariable regions (HVR) of hexon pr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Indonesian Society for Microbiology
2023-01-01
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| Series: | Microbiology Indonesia |
| Online Access: | https://jurnal.permi.or.id/index.php/mionline/article/view/998 |