Regulation of yeast Snf1 (AMPK) by a polyhistidine containing pH sensing module

Summary: Cellular regulation of pH is crucial for internal biological processes and for the import and export of ions and nutrients. In the yeast Saccharomyces cerevisiae, the major proton pump (Pma1) is regulated by glucose. Glucose is also an inhibitor of the energy sensor Snf1/AMPK, which is cons...

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Bibliographic Details
Main Authors: Kobi J. Simpson-Lavy, Martin Kupiec
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013554