Upc2-mediated mechanisms of azole resistance in Candida auris

Upc2-mediated mechanisms of azole resistance in Candida auris

ABSTRACTCandida auris is an emerging yeast pathogen of major concern because of its ability to cause hospital outbreaks of invasive candidiasis and to develop resistance to antifungal drugs. A majority of C. auris isolates are resistant to fluconazole, an azole drug used for the treatment of invasiv...

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Bibliographic Details
Main Authors: Jizhou Li, Lola Aubry, Danielle Brandalise, Alix T. Coste, Dominique Sanglard, Frederic Lamoth
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
ergosterol
efflux pumps
antifungal resistance
zinc cluster transcription factor
Candida albicans
Candida glabrata
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03526-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03526-23

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