Serotonin Receptor Gene Polymorphisms Are Associated with Cerebrospinal Fluid, Genetic, and Neuropsychological Biomarkers of Alzheimer’s Disease

Serotonin Receptor Gene Polymorphisms Are Associated with Cerebrospinal Fluid, Genetic, and Neuropsychological Biomarkers of Alzheimer’s Disease

A decrease in serotonergic transmission throughout the brain is among the earliest pathological changes in Alzheimer’s disease (AD). Serotonergic receptors are also affected in AD. Polymorphisms in genes of serotonin (5HT) receptors have been mostly associated with behavioral and psychological sympt...

Full description

Bibliographic Details
Main Authors: Mirjana Babić Leko, Matea Nikolac Perković, Ena Španić, Dubravka Švob Štrac, Nikolina Pleić, Željka Vogrinc, Ivana Gunjača, Dora Bežovan, Gordana Nedić Erjavec, Nataša Klepac, Fran Borovečki, Tatijana Zemunik, Nela Pivac, Patrick R. Hof, Goran Šimić
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
Alzheimer’s disease
5-hydroxytryptamine (serotonin)
5HT receptors
biomarkers
cerebrospinal fluid
Mini-Mental State Examination
Online Access:https://www.mdpi.com/2227-9059/10/12/3118

Internet

https://www.mdpi.com/2227-9059/10/12/3118

Similar Items