Serotonin Receptor Gene Polymorphisms Are Associated with Cerebrospinal Fluid, Genetic, and Neuropsychological Biomarkers of Alzheimer’s Disease
A decrease in serotonergic transmission throughout the brain is among the earliest pathological changes in Alzheimer’s disease (AD). Serotonergic receptors are also affected in AD. Polymorphisms in genes of serotonin (5HT) receptors have been mostly associated with behavioral and psychological sympt...
Main Authors: | Mirjana Babić Leko, Matea Nikolac Perković, Ena Španić, Dubravka Švob Štrac, Nikolina Pleić, Željka Vogrinc, Ivana Gunjača, Dora Bežovan, Gordana Nedić Erjavec, Nataša Klepac, Fran Borovečki, Tatijana Zemunik, Nela Pivac, Patrick R. Hof, Goran Šimić |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-12-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/12/3118 |
Similar Items
-
Epigenetics of Alzheimer’s Disease
by: Matea Nikolac Perkovic, et al.
Published: (2021-01-01) -
Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and <i>HTR2A</i>, <i>HTR2C</i>, and <i>MAOB</i> Gene Polymorphisms in Asthma
by: Marcela Konjevod, et al.
Published: (2023-05-01) -
The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine
by: Ning Liu, et al.
Published: (2021-07-01) -
<i>SLC6A3</i>, <i>HTR2C</i> and <i>HTR6</i> Gene Polymorphisms and the Risk of Haloperidol-Induced Parkinsonism
by: Gordana Nedic Erjavec, et al.
Published: (2022-12-01) -
The Association of the Polymorphisms in the <i>FUT8</i>-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder
by: Lucija Tudor, et al.
Published: (2023-03-01)