The yeast cell fusion protein Prm1p requires covalent dimerization to promote membrane fusion.

Prm1p is a multipass membrane protein that promotes plasma membrane fusion during yeast mating. The mechanism by which Prm1p and other putative regulators of developmentally controlled cell-cell fusion events facilitate membrane fusion has remained largely elusive. Here, we report that Prm1p forms c...

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Bibliographic Details
Main Authors: Alex Engel, Pablo S Aguilar, Peter Walter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2868043?pdf=render