Interaction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine

Abstract Background The liver plays an important role in production and metabolism of homocysteine (Hcy), which has been reported to be involved in liver injury. In our previous work, we confirm that Hcy can induce liver injury by activating endoplasmic reticulum (ER) stress. However, the underlying...

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Bibliographic Details
Main Authors: Kun Xiao, Shengchao Ma, Long Xu, Ning Ding, Hui Zhang, Lin Xie, Lingbo Xu, Yun Jiao, Huiping Zhang, Yideng Jiang
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Gut Pathogens
Subjects:
Online Access:https://doi.org/10.1186/s13099-021-00455-z