Neuropeptide S and its receptor aggravated asthma via TFEB dependent autophagy in bronchial epithelial cells

Neuropeptide S and its receptor aggravated asthma via TFEB dependent autophagy in bronchial epithelial cells

Abstract Background Asthma is a prevalent respiratory disorder with limited treatment strategy. Neuropeptide S (NPS) is a highly conserved peptide via binding to its receptor NPSR, a susceptibility gene for asthma from genomics studies. However, little is known about the role of NPS-NPSR in the path...

Full description

Bibliographic Details
Main Authors: Zhixu Wang, Peng Zhao, Gen Yan, Aijuan Sun, Li Xu, Jiao Li, Xiaorun Zhai, Xiangcen Liu, Tingting Mei, Yinghua Xuan, Yunjuan Nie
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Respiratory Research
Subjects:
Neuropeptide S
Asthma
Bronchial epithelial cell
Autophagy
TFEB
Online Access:https://doi.org/10.1186/s12931-025-03125-9

Internet

https://doi.org/10.1186/s12931-025-03125-9

Similar Items