Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).

Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).

Classical scrapie is a neurological disorder of the central nervous system (CNS) characterized by the accumulation of an abnormal, partially protease resistant prion protein (PrP(sc)) in the CNS and in some peripheral tissues in domestic small ruminants. Whereas the pathological changes and genetic...

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Bibliographic Details
Main Authors: Cristina Acín, Inmaculada Martín-Burriel, Eva Monleón, Jaber Lyahyai, José Luis Pitarch, Carmen Serrano, Marta Monzón, Pilar Zaragoza, Juan José Badiola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620333?pdf=render

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http://europepmc.org/articles/PMC3620333?pdf=render

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