Sympathoexcitatory Responses to Isometric Handgrip Exercise Are Associated With White Matter Hyperintensities in Middle-Aged and Older Adults

Sympathoexcitatory Responses to Isometric Handgrip Exercise Are Associated With White Matter Hyperintensities in Middle-Aged and Older Adults

Vascular dysfunction may occur prior to declines in cognitive function and accumulation of neuropathology. White matter hyperintensities (WMH) develop due to cerebral ischemia and elevated blood pressure in midlife. The purpose of this study was to evaluate associations between cardiovascular and ce...

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Bibliographic Details
Main Authors: Andrew G. Pearson, Kathleen B. Miller, Adam T. Corkery, Nicole A. Eisenmann, Anna J. Howery, Karly A. Cody, Nathaniel A. Chin, Sterling C. Johnson, Jill N. Barnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
blood pressure
cerebrovascular disease
white matter
cerebral artery blood velocity
cerebrovascular resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.888470/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.888470/full

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