Titania nanospikes activate macrophage phagocytosis by ligand-independent contact stimulation

Abstract Macrophage phagocytosis is an important research target to combat various inflammatory or autoimmune diseases; however, the phenomenon has never been controlled by artificial means. Titania nanospikes created by alkaline etching treatment can tune macrophage polarization toward a M1-like ty...

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Bibliographic Details
Main Authors: Nadia Kartikasari, Masahiro Yamada, Jun Watanabe, Watcharaphol Tiskratok, Xindie He, Hiroshi Egusa
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16214-2