Metabolic Effects of the Waist-To-Hip Ratio Associated Locus <i>GRB14/COBLL1</i> Are Related to <i>GRB14</i> Expression in Adipose Tissue

Metabolic Effects of the Waist-To-Hip Ratio Associated Locus <i>GRB14/COBLL1</i> Are Related to <i>GRB14</i> Expression in Adipose Tissue

<i>GRB14/COBLL1</i> locus has been shown to be associated with body fat distribution (FD), but neither the causal gene nor its role in metabolic diseases has been elucidated. We hypothesize that <i>GRB14/COBLL1</i> may act as the causal genes for FD-related SNPs (rs10195252 a...

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Bibliographic Details
Main Authors: Chang Sun, Franz Förster, Beate Gutsmann, Yusef Moulla, Christine Stroh, Arne Dietrich, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dressler, Michael Stumvoll, Matthias Blüher, Peter Kovacs, Jana Breitfeld, Esther Guiu-Jurado
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>COBLL1</i>
<i>GRB14</i>
rs10195252
rs6738627
adipose tissue
Online Access:https://www.mdpi.com/1422-0067/23/15/8558

Internet

https://www.mdpi.com/1422-0067/23/15/8558

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