Computation of the Likelihood of Joint Site Frequency Spectra Using Orthogonal Polynomials

In population genetics, information about evolutionary forces, e.g., mutation, selection and genetic drift, is often inferred from DNA sequence information. Generally, DNA consists of two long strands of nucleotides or sites that pair via the complementary bases cytosine and guanine (C and G), on th...

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Bibliographic Details
Main Authors: Claus Vogl, Juraj Bergman
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Computation
Subjects:
Online Access:http://www.mdpi.com/2079-3197/4/1/6