Immunohistochemical Expression of Programmed Cell Death Ligand 1 (PD-L1) in Human Cutaneous Malignant Melanoma: A Narrative Review with Historical Perspectives

Immunohistochemical Expression of Programmed Cell Death Ligand 1 (PD-L1) in Human Cutaneous Malignant Melanoma: A Narrative Review with Historical Perspectives

Programmed death-ligand 1 (PD-L1) is the primary ligand of the receptor programmed death-1 (PD-1) which is constitutively expressed or activated in myeloid, lymphoid (T, B and NK), normal epithelial cells, and cancer. The PD-1/PD-L1 interaction is crucial for the physiological development of immunol...

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Bibliographic Details
Main Authors: Gerardo Cazzato, Teresa Lettini, Anna Colagrande, Irma Trilli, Francesca Ambrogio, Carmelo Laface, Paola Parente, Eugenio Maiorano, Giuseppe Ingravallo
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
programmed death-ligand 1
PD-L1
anti-PD-1
nivolumab
pembrolizumab
immunotherapy
Online Access:https://www.mdpi.com/2073-4425/14/6/1252

Internet

https://www.mdpi.com/2073-4425/14/6/1252

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