Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease.

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease.

To develop stem/progenitor cell-based therapy for cystic fibrosis (CF) lung disease, it is first necessary to identify markers of human lung epithelial progenitor/stem cells and to better understand the potential for differentiation into distinct lineages. Here we investigated integrin α6β4 as an ep...

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Bibliographic Details
Main Authors: Xiaopeng Li, Nathan Rossen, Patrick L Sinn, Andrew L Hornick, Benjamin R Steines, Philip H Karp, Sarah E Ernst, Ryan J Adam, Thomas O Moninger, Dana N Levasseur, Joseph Zabner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861522?pdf=render

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http://europepmc.org/articles/PMC3861522?pdf=render

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