Cocultivation of Chinese prescription and intestine microbiota: SJZD alleviated the major symptoms of IBS-D subjects by tuning neurotransmitter metabolism

Cocultivation of Chinese prescription and intestine microbiota: SJZD alleviated the major symptoms of IBS-D subjects by tuning neurotransmitter metabolism

ObjectiveDiarrhea-predominant irritable bowel syndrome (IBS-D) is a recurrent and common disease featuring dysbiotic intestinal microbiota, with limited treatments. Si-Jun-Zi Decoction (SJZD), a classic Chinese prescription, has been extensively used for IBS-D. This work aimed to explore the ex vivo...

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Bibliographic Details
Main Authors: Xiuwen Xia, Ya Xie, Qiaoqiao Chen, Dou Ding, Zongqin Wang, Yaji Xu, Yili Wang, Xiumin Wang, Weijun Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
diarrhea-predominant irritable bowel syndrome (IBS-D)
Si-Jun-Zi decoction (SJZD)
nontargeted metabolomics
16S rRNA gene sequencing
microbiota-herbal cocultivation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1053103/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1053103/full

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