Exosomal miR-182 derived from bone marrow mesenchymal stem cells drives carfilzomib resistance of multiple myeloma cells by targeting SOX6

Exosomal miR-182 derived from bone marrow mesenchymal stem cells drives carfilzomib resistance of multiple myeloma cells by targeting SOX6

Abstract Background Multiple myeloma (MM) is a common hematological malignancy. Drug resistance remains to be a major clinical challenge in MM therapy. In this study, we aim to investigate the functional roles of bone marrow mesenchymal stem cells (BMSC)-derived exosomal miR-182 on the carfilzomib r...

Full description

Bibliographic Details
Main Authors: Shifeng Long, Shengping Long, Honglei He, Liang Luo, Mei Liu, Ting Ding
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Exosomal miR-182
Carfzomil resistance
SOX6
Bone marrow mesenchymal stem cells
Multiple myeloma
Online Access:https://doi.org/10.1186/s13018-023-04399-9

Internet

https://doi.org/10.1186/s13018-023-04399-9

Similar Items