The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?
Abstract Cellular senescence is a state of irreversible cell cycle arrest that can be induced by a variety of potentially oncogenic stimuli, including DNA damage. Hence, senescence has long been considered to suppress tumorigenesis, acting as a guardian of homeostasis. However, recent studies have r...
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | Inflammation and Regeneration |
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| Online Access: | https://doi.org/10.1186/s41232-022-00197-8 |