Trilinolein, a Natural Triacylglycerol, Protects Cerebral Ischemia through Inhibition of Neuronal Apoptosis and Ameliorates Intimal Hyperplasia via Attenuation of Migration and Modulation of Matrix Metalloproteinase-2 and RAS/MEK/ERK Signaling Pathway in VSMCs

Trilinolein, a Natural Triacylglycerol, Protects Cerebral Ischemia through Inhibition of Neuronal Apoptosis and Ameliorates Intimal Hyperplasia via Attenuation of Migration and Modulation of Matrix Metalloproteinase-2 and RAS/MEK/ERK Signaling Pathway in VSMCs

Cerebrovascular disease is one of the leading causes of disability and death worldwide, and seeking a potential treatment is essential. Trilinolein (TriL) is a natural triacylglycerol presented in several plants. The effects of TriL on cerebrovascular diseases such as cerebral ischemia and carotid s...

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Bibliographic Details
Main Authors: Yuh-Fung Chen, Kuo-Jen Wu, Lian-Ru Siao, Huei-Yann Tsai
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
trilinolein
cerebrovascular diseases
cerebral ischemia/reperfusion
intimal hyperplasia
PDGF-BB
Ras/MEK/ERK signaling pathway
Online Access:https://www.mdpi.com/1422-0067/23/21/12820

Internet

https://www.mdpi.com/1422-0067/23/21/12820

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