Therapeutic efficacy and immunological response of CCL5 antagonists in models of contact skin reaction.

Skin-infiltrating T-cells play a predominant role in allergic and inflammatory skin diseases such as atopic dermatitis, psoriasis and allergic contact dermatitis. These T-cells are attracted by several chemotactic factors including the chemokine CCL5/RANTES, a CC chemokine inducing both the migratio...

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Bibliographic Details
Main Authors: Miriam Canavese, Fiorella Altruda, Lorenzo Silengo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806914?pdf=render