Clonal competition assays identify fitness signatures in cancer progression and resistance in multiple myeloma
Abstract Multiple myeloma (MM) is a genetically heterogeneous disease and the management of relapses is one of the biggest clinical challenges. TP53 alterations are established high‐risk markers and are included in the current disease staging criteria. KRAS is the most frequently mutated gene affect...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-07-01
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Series: | HemaSphere |
Online Access: | https://doi.org/10.1002/hem3.110 |