Transient gestational hypothyroxinemia accelerates and enhances ulcerative colitis-like disorder in the male offspring

Transient gestational hypothyroxinemia accelerates and enhances ulcerative colitis-like disorder in the male offspring

IntroductionGestational hypothyroxinemia (HTX) is a condition that occurs frequently at the beginning of pregnancy, and it correlates with cognitive impairment, autism, and attentional deficit in the offspring. Evidence in animal models suggests that gestational HTX can increase the susceptibility o...

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Main Authors: Juan Carlos Rivera, Ma. Cecilia Opazo, Rosario Hernández-Armengol, Oscar Álvarez, María José Mendoza-León, Esteban Caamaño, Sebastian Gatica, Karen Bohmwald, Susan M. Bueno, Pablo A. González, Michel Neunlist, Helene Boudin, Alexis M. Kalergis, Claudia A. Riedel
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
gestational hypothyroxinemia
ulcerative colitis
colon inflammation
immune cells
autoimmunity
radical oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1269121/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1269121/full

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