Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral destruction of platelets and an inappropriate bone marrow production. Although the primary triggering factors of ITP remain unknown, a loss of immune tolerance—mostly represented by a regulatory T-cell defect—allows...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-06-01
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Series: | HemaSphere |
Online Access: | http://journals.lww.com/10.1097/HS9.0000000000000574 |