Bromelain-loaded nanocomposites decrease inflammatory and cytotoxicity effects of gliadin on Caco-2 cells and peripheral blood mononuclear cells of celiac patients

Bromelain-loaded nanocomposites decrease inflammatory and cytotoxicity effects of gliadin on Caco-2 cells and peripheral blood mononuclear cells of celiac patients

Abstract Enzyme therapy can be an appropriate treatment option for celiac disease (CeD). Here, we developed Bromelain-Loaded Nanocomposites (BLNCs) to improve the stability and retention of bromelain enzyme activity. After the characterization of BLNCs, the cytotoxicity of BLNCs was determined on th...

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Bibliographic Details
Main Authors: Masoumeh Sadat Mousavi Maleki, Ramin Ebrahimi kiasari, Seyed Javad Seyed Mousavi, Hamid Hashemi‐Moghaddam, Ali Akbar Shabani, Hamid Madanchi, Soroush Sardari
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48460-3

Internet

https://doi.org/10.1038/s41598-023-48460-3

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