Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses

Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses

Abstract Background A major goal in the discovery of cellular signaling networks is to identify regulated phosphorylation sites (“phosphosites”) and map them to the responsible protein kinases. The V2 vasopressin receptor is a G-protein coupled receptor (GPCR) that is responsible for regulation of r...

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Bibliographic Details
Main Authors: Kirby T. Leo, Chung-Lin Chou, Chin-Rang Yang, Euijung Park, Viswanathan Raghuram, Mark A. Knepper
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell Communication and Signaling
Subjects:
Protein kinase
V2 vasopressin receptor
Collecting duct
Bayes’ Theorem
Phosphoproteomics
Online Access:https://doi.org/10.1186/s12964-022-00892-6

Internet

https://doi.org/10.1186/s12964-022-00892-6

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