Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse

Apoptosis occurs in numerous developmental processes but a role for necrosis in development is unclear. Here, the authors develop a detecting system of necrosis in the developing mouse and find a form of necrosis that is dependent on the autophagy-related gene Atg9a.

Bibliographic Details
Main Authors: Yusuke Imagawa, Tatsuya Saitoh, Yoshihide Tsujimoto
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13391