Neonatal Cardiovascular-Progenitor-Cell-Derived Extracellular Vesicles Activate YAP1 in Adult Cardiac Progenitor Cells

Neonatal Cardiovascular-Progenitor-Cell-Derived Extracellular Vesicles Activate YAP1 in Adult Cardiac Progenitor Cells

New stem cell and extracellular-vesicle-based therapies have the potential to improve outcomes for the increasing number of patients with heart failure. Since neonates have a significantly enhanced regenerative ability, we hypothesized that extracellular vesicles isolated from Islet-1+ expressing ne...

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Bibliographic Details
Main Authors: Lourdes Ceja, Sean S. Escopete, Lorelei Hughes, Larry V. Lopez, Victor Camberos, Paul Vallejos, Nathan R. Wall, Mary Kearns-Jonker
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
cardiac progenitor cells
neonates
Islet-1
extracellular vesicle
cardiac repair
miRNAs
Online Access:https://www.mdpi.com/1422-0067/24/9/8088

Internet

https://www.mdpi.com/1422-0067/24/9/8088

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