Anti-nociceptive effects of low dose ketamine in mice may be mediated by the serotonergic systems
OBJECTIVE: In pain management, alternative medications are necessary due to the development of tolerance to traditional opioid analgesics. Literature data suggest that N-methyl-D-aspartate (NMDA) receptor antagonizing drugs can induce antinociception, and can reduce the opioid requirement. Ketamine...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
AVES
2019-07-01
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Series: | Psychiatry and Clinical Psychopharmacology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/24750573.2019.1605665 |