The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel
Summary: Repaglinide (RPG) is a short-acting insulin secretagogue widely prescribed for the treatment of type 2 diabetes. It boosts insulin secretion by inhibiting the pancreatic ATP-sensitive potassium channel (KATP). However, the mechanisms by which RPG binds to the KATP channel are poorly underst...
| Auteurs principaux: | , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Elsevier
2019-05-01
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| Collection: | Cell Reports |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2211124719305236 |