Concatemeric Broccoli reduces mRNA stability and induces aggregates.

Concatemeric Broccoli reduces mRNA stability and induces aggregates.

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Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fused to an mCherry-coding mRNA in transient transfe...

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Bibliographic Details
Main Authors: Marco R Rink, Marisa A P Baptista, Felix J Flomm, Thomas Hennig, Adam W Whisnant, Natalia Wolf, Jürgen Seibel, Lars Dölken, Jens B Bosse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244166

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https://doi.org/10.1371/journal.pone.0244166

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