Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast

<p>Abstract</p> <p>Background</p> <p>Carcinoma-associated fibroblasts (CAFs) can promote carcinogenesis and tumor progression. Only limited data on the response of CAFs to chemotherapy and their potential impact on therapy outcome are available. This study was undertake...

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Bibliographic Details
Main Authors: Simon Wolfgang, Friedel Godehard, Schroth Werner, Fritz Peter, Haubeiß Silke, van der Kuip Heiko, Sonnenberg Maike, Mürdter Thomas E, Aulitzky Walter E
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/364